Detection of inducible clindamycin resistance among Staphylococcal isolates from different clinical specimens in western India

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Inducible Clindamycin Resistance among Clinical Isolates of Staphylococcus aureus from Sub Himalayan Region of India.

INTRODUCTION Clindamycin is an alternative antibiotic in the treatment of Staphylococcus aureus (S.aureus) infections, both in infections by methicillin susceptible and resistant (MSSA and MRSA) strains. The major problem of use of clindamycin for staphylococcal infections is the presence of inducible clindamycin resistance that can lead to treatment failure in such infections. AIM To determi...

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Inducible clindamycin resistance among clinical isolates of Staphylococci.

INTRODUCTION Clinical failure of clindamycin therapy has been reported due to multiple mechanisms that confer resistance to macrolide, lincosamide and streptogramin antibiotics. This study was undertaken to detect the presence of inducible clindamycin resistance among clinical isolates of staphylococci. MATERIALS AND METHODS The detection of inducible clindamycin resistance was performed by D...

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Inducible clindamycin resistance among Staphylococcus aureus isolates

Introduction: Clindamycin is considered an useful alternate drug in penicillin-allergic patients in the treatment of skin & soft tissue infections caused by Staphylococcus aureus. Staphylococcus spp. can be resistant to erythromycin through either erm or msr A genes. Strains with erm-mediated erythromycin resistance may possess inducible clindamycin resistance but may appear susceptible to clin...

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Prevalence of inducible clindamycin resistance among community-associated staphylococcal isolates in central Serbia.

The emergence of resistance to most antimicrobial agents in staphylococci indicates the need for new effective agents in the treatment of staphylococcal infections. Clindamycin is considered to be one safe, effective and less costly agent. We analysed 482 staphylococcal isolates. Detection of inducible clindamycin resistance was performed by the D-test, while the presence of methylases genes: e...

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inducible clindamycin resistance in clinical isolates of staphylococcus aureus

conclusions in our study, inducible clindamycin resistance rate was 4%; so it is necessary to conduct d-test regularly by disc diffusion for this bacterium. resistance to erythromycin, clindamycin, ciprofloxacin and gentamicin was significantly higher in mrsa isolates than methicillin susceptible staphylococcus aureus (mssa), although the methicillin resistance prevalence was low. background st...

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ژورنال

عنوان ژورنال: Journal of Postgraduate Medicine

سال: 2010

ISSN: 0022-3859

DOI: 10.4103/0022-3859.68637